Comparative Sequence Analysis

S M A R T Simple Modular Architecture Research Tool (V1.03)

Clicking on any of the highlighted domain names at the SMART Homepage will lead to display of this first type of annotation page.

The output is similar to figure 1 presented below.

Figure 1

In addition to comment lines, we present links to relevant Medline, MMDB and Prosite entries.

There are 3 services that may be requested from these pages:

View the domain family alignment using different formats
This allows display of the full seed alignment of the domain family.
View the consensus sequence of the family
This displays consensus sequences using thresholds of 80%, 65% and 50%, and amino acid groupings that are displayed elsewhere.
Retrieve annotations of other domains
Currently annotated domains are listed at the foot of each page and access to their annotation pages are provided by hyperlinks.

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