| Domain name | Description | Inserted |
| HWE_HK | HWE histidine kinase | 2009-05-07 |
| HIRAN | | 2009-05-07 |
| Haemagg_act | haemagglutination activity domain | 2009-05-07 |
| Fungal_trans | Fungal specific transcription factor domain | 2009-05-07 |
| GDNF | GDNF/GAS1 domain | 2009-05-07 |
| Gal-bind_lectin | Galactoside-binding lectin | 2009-05-07 |
| Germane | Sporulation and spore germination | 2009-05-07 |
| Malic_M | Malic enzyme, NAD binding domain | 2009-05-14 |
| IBN_N | Importin-beta N-terminal domain | 2009-05-14 |
| IDEAL | | 2009-05-14 |
| LeuA_dimer | LeuA allosteric (dimerisation) domain | 2009-05-14 |
| MHC_II_beta | Class II histocompatibility antigen, beta domain | 2009-05-14 |
| MbtH | MbtH-like protein | 2009-05-14 |
| NADH-G_4Fe-4S_3 | NADH-ubiquinone oxidoreductase-G iron-sulfur binding region | 2009-05-14 |
| Jacalin | Jacalin-like lectin domain | 2009-05-14 |
| L51_S25_CI-B8 | Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain | 2009-05-14 |
| Lig_chan-Glu_bd | Ligated ion channel L-glutamate- and glycine-binding site | 2009-05-14 |
| MHC_II_alpha | Class II histocompatibility antigen, alpha domain | 2009-05-14 |
| MR_MLE | Mandelate racemase / muconate lactonizing enzyme, C-terminal domain | 2009-05-14 |
| MltA | MltA specific insert domain | 2009-05-14 |
| MgtE_N | MgtE intracellular N domain | 2009-05-14 |
| Molybdop_Fe4S4 | Molybdopterin oxidoreductase Fe4S4 domain | 2009-05-14 |
| NADH_4Fe-4S | NADH-ubiquinone oxidoreductase-F iron-sulfur binding region | 2009-05-14 |
| Nfu_N | Scaffold protein Nfu/NifU N terminal | 2009-05-14 |
| MutH | DNA mismatch repair enzyme MutH | 2009-05-14 |
| NIL | | 2009-05-14 |
| NOSIC | NOSIC (NUC001) domain | 2009-05-14 |
| RES | | 2009-07-28 |
| PepX_C | X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain | 2009-07-28 |
| PepX_N | X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal | 2009-07-28 |
| PriCT_1 | Primase C terminal 1 (PriCT-1) | 2009-07-28 |
| ProQ | ProQ/FINO family | 2009-07-28 |
| ProRS-C_1 | Prolyl-tRNA synthetase, C-terminal | 2009-07-28 |
| PAZ | | 2009-07-28 |
| QLQ | | 2009-07-28 |
| RelA_SpoT | Region found in RelA / SpoT proteins | 2009-07-28 |
| NurA | | 2009-07-28 |
| OMPdecase | Orotidine 5'-phosphate decarboxylase / HUMPS family | 2009-07-28 |
| OmpH | Outer membrane protein (OmpH-like) | 2009-07-28 |
| PBP5_C | Penicillin-binding protein 5, C-terminal domain | 2009-07-28 |
| PCRF | | 2009-07-28 |
| P-II | Nitrogen regulatory protein P-II | 2009-07-28 |
| PYNP_C | Pyrimidine nucleoside phosphorylase C-terminal domain | 2009-07-28 |
| Prim-Pol | Bifunctional DNA primase/polymerase, N-terminal | 2009-07-28 |
| Pro-kuma_activ | Pro-kumamolisin, activation domain | 2009-07-28 |
| Pro_CA | Carbonic anhydrase | 2009-07-28 |
| Proteasome_A_N | Proteasome subunit A N-terminal signature Add an annotation | 2009-07-28 |
| Piwi | | 2009-07-28 |
| RAP | | 2009-07-28 |
| SRP54_N | SRP54-type protein, helical bundle domain | 2009-11-18 |
| STAT_int | STAT protein, protein interaction domain | 2009-11-18 |
| STN | Secretin and TonB N terminus short domain | 2009-11-18 |
| SpoVT_AbrB | SpoVT / AbrB like domain | 2009-11-18 |
| SpoU_sub_bind | RNA 2'-O ribose methyltransferase substrate binding | 2009-11-18 |
| s48_45 | Sexual stage antigen s48/45 domain | 2009-11-18 |
| SATase_N | Serine acetyltransferase, N-terminal | 2009-11-18 |
| SCPU | Spore Coat Protein U domain | 2009-11-18 |
| Sec63 | Sec63 Brl domain | 2009-11-18 |
| Telo_bind | Telomeric single stranded DNA binding POT1/CDC13 | 2009-11-18 |
| TilS_C | TilS substrate C-terminal domain | 2009-11-18 |
| Tim44 | | 2009-11-18 |
| THAP | | 2009-11-18 |
| RNB | | 2009-11-18 |
| RQC | | 2009-11-18 |
| SecA_DEAD | SecA DEAD-like domain | 2009-11-18 |
| SecA_PP_bind | SecA preprotein cross-linking domain | 2009-11-18 |
| Robl_LC7 | Roadblock/LC7 domain | 2009-11-18 |
| SOCS_box | | 2009-11-18 |
| T5orf172 | | 2009-11-18 |
| THUMP | | 2009-11-18 |
| Rho_N | Rho termination factor, N-terminal domain | 2009-11-18 |
| RuBisCO_small | Ribulose bisphosphate carboxylase, small chain | 2009-11-18 |
| SRP54 | SRP54-type protein, GTPase domain | 2009-11-18 |
| SMC_hinge | SMC proteins Flexible Hinge Domain | 2009-11-18 |
| Telomerase_RBD | Telomerase ribonucleoprotein complex - RNA binding domain | 2009-11-18 |
| TIFY | | 2009-11-18 |