NMU

Neuromedin U
NMU
SMART accession number:SM00084
Description: Neuromedin U (NmU) is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active peptides, it is proteolytically processed from a larger precursor protein. The mature peptides are 8 (NmU-8) to 25 (NmU-25) residues long and C- terminally amidated. The sequence of the C-terminal extremity of NmU is extremely well conserved in mammals, birds and amphibians.
Interpro abstract (IPR008200):

Neuromedin U (NmU) [(PUBMED:3239891), (PUBMED:1455013)] is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active peptides, it is proteolytically processed from a larger precursor protein. The mature peptides are 8 (NmU-8) to 25 (NmU-25) residues long and C-terminally amidated.

This entry represents the sequence of the C-terminal extremity of NmU, which is extremely well conserved.

GO process:regulation of smooth muscle contraction (GO:0006940)
Family alignment:
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There are 17 NMU domains in 17 proteins in SMART's nrdb database.

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