|SMART accession number:||SM00183
||Atrial natriuretic peptides are vertebrate hormones important in the overall control of cardiovascular homeostasis and sodium and water balance in general. |
|Interpro abstract (IPR000663):
||Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control of cardiovascular homeostatis, and sodium and water balance in general [(PUBMED:1652921), (PUBMED:2536732)]. There are different NPs that vary in length but share a common core. All are processed from a single precursor. A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The family of NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these are brain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP) [(PUBMED:1828035)]; and green mamba natriuretic peptide (DNP) [(PUBMED:1352773)].
|GO component:||extracellular region (GO:0005576)|
|GO function:||hormone activity (GO:0005179)|
There are 520 NAT_PEP domains in 473 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)