CAD

Domains present in proteins implicated in post-mortem DNA fragmentation
CAD
SMART accession number:SM00266
Description:
Interpro abstract (IPR003508):

This domain consists of caspase-activated (CAD) nucleases, which induce DNA fragmentation and chromatin condensation during apoptosis, and the cell death activator proteins CIDE-A and CIDE-B, which are inhibitors of CAD nuclease. The two proteins interact through the region defined by the method signatures.

GO process:apoptotic process (GO:0006915)
GO component:intracellular (GO:0005622)
Family alignment:
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There are 155 CAD domains in 155 proteins in SMART's nrdb database.

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