WR1

Worm-specific repeat type 1
WR1
SMART accession number:SM00289
Description: Worm-specific repeat type 1. Cysteine-rich domain apparently unique (so far) to C. elegans. Often appears with KU domains. About 3 dozen worm proteins contain this domain.
Interpro abstract (IPR006150):

This repeat, originally named as Worm-specific repeat type 1, is found in several Caenorhabditis elegans proteins, as well as some other eukaryotes. The region contains several conserved cysteines that probably form disulphide bridges and is often found associated with kunitz domains IPR002223 that may function as serine peptidase inhibitors; these belong to MEROPS peptidase inhibitor family I2.

Family alignment:
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There are 889 WR1 domains in 249 proteins in SMART's nrdb database.

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