G_patch

glycine rich nucleic binding domain
G_patch
SMART accession number:SM00443
Description: A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.
Interpro abstract (IPR000467): The G-patch domain [(PUBMED:10470032)] is a short conserved region of about 40 amino acids which occurs in a number of putative RNA-binding proteins, including tumor suppressor and DNA-damage-repair proteins, suggesting that this domain may have an RNA binding function. This domain has seven highly conserved glycines. A multiple alignment of a small subset of G-patch domains is shown in Fig. 2b of [(PUBMED:10353602)].
GO function:nucleic acid binding (GO:0003676)
Family alignment:
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There are 2124 G_patch domains in 2115 proteins in SMART's nrdb database.

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