ParB

ParB-like nuclease domain
ParB
SMART accession number:SM00470
Description: Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded character, like AT-rich regions and sequences that can form cruciform structures. ParB also exhibits 5-->3 exonuclease activity.
Interpro abstract (IPR003115): Proteins containing this domain, appear to be related to the Escherichia coli plasmid protein ParB, which preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded character, like AT-rich regions and sequences that can form cruciform structures. ParB also exhibits 5--3 exonuclease activity.
GO function:DNA binding (GO:0003677)
Family alignment:
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There are 3223 ParB domains in 3222 proteins in SMART's nrdb database.

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