• Links (links to other resources describing this domain)
  • POLAc

    DNA polymerase A domain
    SMART accession number:SM00482
    Description: -
    Interpro abstract (IPR001098): Synonym(s): DNA nucleotidyltransferase (DNA-directed)

    DNA-directed DNA polymerases(EC are the key enzymes catalysing the accurate replication of DNA. They require either a small RNA molecule or a protein as a primer for the de novo synthesis of a DNA chain. A number of polymerases belong to this family [(PUBMED:2196557), (PUBMED:1870963), (PUBMED:8451181)].

    GO process:DNA replication (GO:0006260)
    GO function:DNA-directed DNA polymerase activity (GO:0003887), DNA binding (GO:0003677)
    Family alignment:
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    There are 8351 POLAc domains in 8351 proteins in SMART's nrdb database.

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