SMART: ChtBD3 domain annotation

ChtBD3 Chitin-binding domain type 3

SMART accession number:	SM00495
Description:
Interpro abstract (IPR003610):	The carbohydrate-binding domain (CBD) is a short domain found in many different glycosyl hydrolase enzymes, such as the C-terminal cellulose-binding domain of endoglucanase Z (PUBMED:9405041). The domain has a core structure consisting of a 3-stranded meander beta-sheet, which contains six aromatic groups that may be important for binding. The overall topology of the CBD is structurally similar to the C-terminal chitin-binding domains (ChBD) of chitinase A1 and chitinase B, however the binding mechanism for the ChBD may be different from that of the CBD (PUBMED:10788483).
GO process:	carbohydrate metabolic process (GO:0005975)
GO component:	extracellular region (GO:0005576)
GO function:	carbohydrate binding (GO:0030246), hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)
Family alignment:	View or

There are 788 ChtBD3 domains in 499 proteins in SMART's nrdb database.

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Evolution (species in which this domain is found)
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Metabolism (metabolic pathways involving proteins which contain this domain)

Structure (3D structures containing this domain)

3D Structures of ChtBD3 domains in PDB

PDB code	Main view	Title
1aiw		Nmr structures of the cellulose-binding domain of the endoglucanase z from erwinia chrysanthemi, 23 structures
1e15		Chitinase b from serratia marcescens
1e6n		Chitinase b from serratia marcescens inactive mutant e144q in complex with n-acetylglucosamine-pentamer
1e6p		Chitinase b from serratia marcescens inactive mutant e144q
1e6r		Chitinase b from serratia marcescens wildtype in complex with inhibitor allosamidin
1e6z		Chitinase b from serratia marcescens wildtype in complex with catalytic intermediate
1ed7		Solution structure of the chitin-binding domain of bacillus circulans wl-12 chitinase a1
1goi		Crystal structure of the d140n mutant of chitinase b from serratia marcescens at 1.45 a resolution
1gpf		Chitinase b from serratia marcescens in complex with inhibitor psammaplin
1h0g		Complex of a chitinase with the natural product cyclopentapeptide argadin from clonostachys
1h0i		Complex of a chitinase with the natural product cyclopentapeptide argifin from gliocladiu
1o6i		Chitinase b from serratia marcescens complexed with the catalytic intermediate mimic cyclic dipeptide ci4.
1ogb		Chitinase b from serratia marcescens mutant d142n
1ogg		Chitinase b from serratia marcescens mutant d142n in complex with inhibitor allosamidin
1ur8		Interactions of a family 18 chitinase with the designed inhibitor hm508, and its degradation product, chitobiono- delta-lactone
1ur9		Interactions of a family 18 chitinase with the designed inhibitor hm508, and its degradation product, chitobiono- delta-lactone
1w1p		Crystal structure of s. marcescens chitinase b in complex with the cyclic dipeptide inhibitor cyclo-(gly-l-pro) at 2.1 a resolution
1w1t		Crystal structure of s. marcescens chitinase b in complex with the cyclic dipeptide inhibitor cyclo-(his-l-pro) at 1.9 a resolution
1w1v		Crystal structure of s. marcescens chitinase b in complex with the cyclic dipeptide inhibitor cyclo-(l-arg-l-pro) at 1.85 a resolution
1w1y		Crystal structure of s. marcescens chitinase b in complex with the cyclic dipeptide inhibitor cyclo-(l-tyr-l-pro) at 1.85 a resolution
1wvu		Crystal structure of chitinase c from streptomyces griseus hut6037
1wvv		Crystal structure of chitinase c mutant e147q
2d49		Solution structure of the chitin-binding domain of streptomyces griseus chitinase c
2dbt		Crystal structure of chitinase c from streptomyces griseus hut6037

Links (links to other resources describing this domain)
INTERPRO IPR003610