BASIC

Basic domain in HLH proteins of MYOD family
BASIC
SMART accession number:SM00520
Description: -
Interpro abstract (IPR002546): This basic domain is found in the MyoD family of muscle specific proteins that control muscle development. The bHLH region of the MyoD family includes the basic domain and the Helix-loop-helix (HLH) motif. The bHLH region mediates specific DNA binding [(PUBMED:9343420)]. With 12 residues of the basic domain involved in DNA binding [(PUBMED:8790335)]. The basic domain forms an extended alpha helix in the structure.
GO process:regulation of transcription, DNA-templated (GO:0006355), muscle organ development (GO:0007517)
GO component:nucleus (GO:0005634)
GO function:DNA binding (GO:0003677)
Family alignment:
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There are 589 BASIC domains in 548 proteins in SMART's nrdb database.

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