IROMotif in Iroquois-class homeodomain proteins (only). Unknown function.
|SMART accession number:||SM00548
|Interpro abstract (IPR003893):
||This is a motif found only in Iroquois-class homeodomain proteins. It has unknown function. Examples include iroquois-class homeodomain protein IRX-4, and homeobox proteins caupolican and araucan, which control proneural and vein forming genesand are positive transcriptional controllers of achaete-scute. They may act as activators that interact with the transcriptional initiation complex assembled on the achaete and scute promoters.
|GO process:||regulation of transcription, DNA-dependent (GO:0006355)|
|GO component:||nucleus (GO:0005634)|
|GO function:||DNA binding (GO:0003677)|
There are 189
IRO domains in 189 proteins in SMART's nrdb database.
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- Evolution (species in which this domain is found)
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