IRO

Motif in Iroquois-class homeodomain proteins (only). Unknown function.
IRO
SMART accession number:SM00548
Description: -
Interpro abstract (IPR003893): This is a motif found only in Iroquois-class homeodomain proteins. It has unknown function. Examples include iroquois-class homeodomain protein IRX-4, and homeobox proteins caupolican and araucan, which control proneural and vein forming genesand are positive transcriptional controllers of achaete-scute. They may act as activators that interact with the transcriptional initiation complex assembled on the achaete and scute promoters.
GO process:regulation of transcription, DNA-templated (GO:0006355)
GO component:nucleus (GO:0005634)
GO function:DNA binding (GO:0003677)
Family alignment:
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There are 600 IRO domains in 600 proteins in SMART's nrdb database.

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