RL11Ribosomal protein L11/L12 |
 |
|---|
| SMART accession number: | SM00649 |
|---|---|
| Description: | |
| Interpro abstract (IPR000911): | Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites [(PUBMED:11297922), (PUBMED:11290319)]. About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they belong to - the small (S1 to S31) and the large (L1 to L44). Usually they decorate the rRNA cores of the subunits. Many ribosomal proteins, particularly those of the large subunit, are composed of a globular, surfaced-exposed domain with long finger-like projections that extend into the rRNA core to stabilise its structure. Most of the proteins interact with multiple RNA elements, often from different domains. In the large subunit, about 1/3 of the 23S rRNA nucleotides are at least in van der Waal's contact with protein, and L22 interacts with all six domains of the 23S rRNA. Proteins S4 and S7, which initiate assembly of the 16S rRNA, are located at junctions of five and four RNA helices, respectively. In this way proteins serve to organise and stabilise the rRNA tertiary structure. While the crucial activities of decoding and peptide transfer are RNA based, proteins play an active role in functions that may have evolved to streamline the process of protein synthesis. In addition to their function in the ribosome, many ribosomal proteins have some function 'outside' the ribosome [(PUBMED:11290319), (PUBMED:11114498)]. Ribosomal protein L11 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L11 is known to bind directly to the 23S rRNA. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [(PUBMED:2167467), ], groups bacteria, plant chloroplast, red algal chloroplast, cyanelle and archaeabacterial L11; and mammalian, plant and yeast L12 (YL15). L11 is a protein of 140 to 165 amino-acid residues. In E. coli, the C-terminal half of L11 has been shown [(PUBMED:2483975)] to be in an extended and loosely folded conformation and is likely to be buried within the ribosomal structure. |
| GO process: | translation (GO:0006412) |
| GO component: | ribosome (GO:0005840) |
| GO function: | structural constituent of ribosome (GO:0003735) |
| Family alignment: |
There are 1846 RL11 domains in 1846 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
-
Click on
to expand nodes. To display all proteins with a RL11 domain in a specific node, click on it.This tree shows only several representative species. The complete taxonomic breakdown of all proteins with RL11 domain is also avaliable.
Useful shortcuts: Expand all nodes or Collapse tree
Go to specific node: Anopheles gambiae, Arabidopsis thaliana, Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae, Takifugu rubripes - Cellular role (predicted cellular role)
-
Cellular role: translation
Binding / catalysis: RNA-binding - Literature (relevant references for this domain)
-
Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Markus MA, Gerstner RB, Draper DE, Torchia DA
- The solution structure of ribosomal protein S4 delta41 reveals two subdomains and a positively charged surface that may interact with RNA.
- EMBO J. 1998; 17: 4559-71
- Display abstract
S4 is one of the first proteins to bind to 16S RNA during assembly of the prokaryotic ribosome. Residues 43-200 of S4 from Bacillus stearothermophilus (S4 Delta41) bind specifically to both 16S rRNA and to a pseudoknot within the alpha operon mRNA. As a first step toward understanding how S4 recognizes and organizes RNA, we have solved the structure of S4 Delta41 in solution by multidimensional heteronuclear nuclear magnetic resonance spectroscopy. The fold consists of two globular subdomains, one comprised of four helices and the other comprised of a five-stranded antiparallel beta-sheet and three helices. Although cross-linking studies suggest that residues between helices alpha2 and alpha3 are close to RNA, the concentration of positive charge along the crevice between the two subdomains suggests that this could be an RNA-binding site. In contrast to the L11 RNA-binding domain studied previously, S4 Delta41 shows no fast local motions, suggesting that it has less capacity for refolding to fit RNA. The independently determined crystal structure of S4 Delta41 shows similar features, although there is small rotation of the subdomains compared with the solution structure. The relative orientation of the subdomains in solution will be verified with further study.
- Metabolism (metabolic pathways involving proteins which contain this domain)
-
Click the image to view the interactive version of the map in iPath% proteins involved KEGG pathway ID Description 97.84 map03010 Ribosome 0.27 
map00120Bile acid biosynthesis 0.27 map00350Tyrosine metabolism 0.27 map00980 Metabolism of xenobiotics by cytochrome P450 0.27 map00010Glycolysis / Gluconeogenesis 0.27 map006413-Chloroacrylic acid degradation 0.27 map00561Glycerolipid metabolism 0.27 map006241- and 2-Methylnaphthalene degradation 0.27 map00071Fatty acid metabolism This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with RL11 domain which could be assigned to a KEGG orthologous group, and not all proteins containing RL11 domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.
- Structure (3D structures containing this domain)
3D Structures of RL11 domains in PDB
PDB code Main view Title 1aci 
L11 ribosomal protein rna binding domain, nmr, 20 structures 1c04 
Identification of known protein and rna structures in a 5 a map of the large ribosomal subunit from haloarcula marismortui 1eg0 
Fitting of components with known structure into an 11.5 a cryo-em map of the e.coli 70s ribosome 1fow 
Nmr structure of l11-c76, the c-terminal domain of 50s ribosomal protein l11, minimized average structure 1fox 
Nmr structure of l11-c76, the c-terminal domain of 50s ribosomal protein l11, 33 structures 1foy 
The rna binding domain of ribosomal protein l11: three- dimensional structure of the rna-bound form of the protein, nmr, minimized average structure 1giy 
Crystal structure of the ribosome at 5.5 a resolution. this file, 1giy, contains the 50s ribosome subunit. the 30s ribosome subunit, three trna, and mrna molecules are in the file 1gix 1hc8 
Crystal structure of a conserved ribosomal protein-rna complex 1jqm 
Fitting of l11 protein and elongation factor g (ef-g) in the cryo-em map of e. coli 70s ribosome bound with ef-g, gdp and fusidic acid 1jqs 
Fitting of l11 protein and elongation factor g (domain g' and v) in the cryo-em map of e. coli 70s ribosome bound with ef-g and gmppcp, a nonhydrolysable gtp analog 1jqt 
Fitting of l11 protein in the low resolution cryo-em map of e.coli 70s ribosome 1mj1 
Fitting the ternary complex of ef-tu/trna/gtp and ribosomal proteins into a 13 a cryo-em map of the coli 70s ribosome 1mms 
Crystal structure of the ribosomal protein l11-rna complex 1mvr 
Decoding center & peptidyl transferase center from the x- ray structure of the thermus thermophilus 70s ribosome, aligned to the low resolution cryo-em map of e.coli 70s ribosome 1nkw 
Crystal structure of the large ribosomal subunit from deinococcus radiodurans 1nwx 
Complex of the large ribosomal subunit from deinococcus radiodurans with abt-773 1nwy 
Complex of the large ribosomal subunit from deinococcus radiodurans with azithromycin 1oln 
Model for thiostrepton antibiotic binding to l11 substrate from 50s ribosomal rna 1p85 
Real space refined coordinates of the 50s subunit fitted into the low resolution cryo-em map of the ef-g.gtp state of e. coli 70s ribosome 1p86 
Real space refined coordinates of the 50s subunit fitted into the low resolution cryo-em map of the initiation-like state of e. coli 70s ribosome 1pn7 
Coordinates of s12, l11 proteins and p-trna, from the 70s x- ray structure aligned to the 70s cryo-em map of e.coli ribosome 1pn8 
Coordinates of s12, l11 proteins and e-site trna from 70s crystal structure separately fitted into the cryo-em map of e.coli 70s.ef-g.gdpnp complex. the atomic coordinates originally from the e-site trna were fitted in the position of the hybrid p/e-site trna. 1pnu 
Crystal structure of a streptomycin dependent ribosome from escherichia coli, 50s subunit of 70s ribosome. this file, 1pnu, contains only molecules of the 50s ribosomal subunit. the 30s subunit, mrna, p-site trna, and a-site trna are in the pdb file 1pns. 1pny 
Crystal structure of the wild type ribosome from e. coli, 50s subunit of 70s ribosome. this file, 1pny, contains only molecules of the 50s ribosomal subunit. the 30s subunit is in the pdb file 1pnx. 1qa6 
Crystal structure of a conserved ribosomal protein-rna complex 1r2w 
Coordinates of l11 with 58nts of 23s rrna fitted into the cryo-em map of the 70s ribosome 1r2x 
Coordinates of l11 with 58nts of 23s rrna fitted into the cryo-em map of ef-tu ternary complex (gdp.kirromycin) bound 70s ribosome 1s1i 
Structure of the ribosomal 80s-eef2-sordarin complex from yeast obtained by docking atomic models for rna and protein components into a 11.7 a cryo-em map. this file, 1s1i, contains 60s subunit. the 40s ribosomal subunit is in file 1s1h. 1s72 
Refined crystal structure of the haloarcula marismortui large ribosomal subunit at 2.4 angstrom resolution 1sm1 
Complex of the large ribosomal subunit from deinococcus radiodurans with quinupristin and dalfopristin 1vor 
Crystal structure of five 70s ribosomes from escherichia coli in complex with protein y. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains five 70s ribosomes and is described in remark 400. 1vou 
Crystal structure of five 70s ribosomes from escherichia coli in complex with protein y. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains five 70s ribosomes and is described in remark 400. 1vow 
Crystal structure of five 70s ribosomes from escherichia coli in complex with protein y. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains five 70s ribosomes and is described in remark 400. 1voy 
Crystal structure of five 70s ribosomes from escherichia coli in complex with protein y. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains five 70s ribosomes and is described in remark 400. 1vp0 
Crystal structure of five 70s ribosomes from escherichia coli in complex with protein y. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains five 70s ribosomes and is described in remark 400. 1vq4 
The structure of the transition state analogue "daa" bound to the large ribosomal subunit of haloarcula marismortui 1vq5 
The structure of the transition state analogue "raa" bound to the large ribosomal subunit of haloarcula marismortui 1vq6 
The structure of c-hpmn and cca-phe-cap-bio bound to the large ribosomal subunit of haloarcula marismortui 1vq7 
The structure of the transition state analogue "dca" bound to the large ribosomal subunit of haloarcula marismortui 1vq8 
The structure of ccda-phe-cap-bio and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui 1vq9 
The structure of cca-phe-cap-bio and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui 1vqk 
The structure of ccda-phe-cap-bio bound to the a site of the ribosomal subunit of haloarcula marismortui 1vql 
The structure of the transition state analogue "dcsn" bound to the large ribosomal subunit of haloarcula marismortui 1vqm 
The structure of the transition state analogue "dan" bound to the large ribosomal subunit of haloarcula marismortui 1vqn 
The structure of cc-hpmn and cca-phe-cap-bio bound to the large ribosomal subunit of haloarcula marismortui 1vqo 
The structure of ccpmn bound to the large ribosomal subunit haloarcula marismortui 1vqp 
The structure of the transition state analogue "rap" bound to the large ribosomal subunit of haloarcula marismortui 1vs6 
Crystal structure of the bacterial ribosome from escherichia coli in complex with the antibiotic kasugamyin at 3.5a resolution. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 1vs8 
Crystal structure of the bacterial ribosome from escherichia coli in complex with the antibiotic kasugamyin at 3.5a resolution. this file contains the 30s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 1wib 
Solution structure of the n-terminal domain from mouse hypothetical protein bab22488 1xbp 
Inhibition of peptide bond formation by pleuromutilins: the structure of the 50s ribosomal subunit from deinococcus radiodurans in complex with tiamulin 1y39 
Co-evolution of protein and rna structures within a highly conserved ribosomal domain 1yhq 
Crystal structure of azithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui 1yi2 
Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui 1yij 
Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui 1yit 
Crystal structure of virginiamycin m and s bound to the 50s ribosomal subunit of haloarcula marismortui 1yj9 
Crystal structure of the mutant 50s ribosomal subunit of haloarcula marismortui containing a three residue deletion in l22 1yjn 
Crystal structure of clindamycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui 1yjw 
Crystal structure of quinupristin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui 1yl3 
Crystal structure of 70s ribosome with thrs operator and trnas. large subunit. the coordinates for the small subunit are in the pdb entry 1yl4. 2aw4 
Crystal structure of the bacterial ribosome from escherichia coli at 3.5 a resolution. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2awb 
Crystal structure of the bacterial ribosome from escherichia coli at 3.5 a resolution. this file contains the 50s subunit of the second 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2b66 
50s ribosomal subunit from a crystal structure of release factor rf1, trnas and mrna bound to the ribosome. this file contains the 50s subunit from a crystal structure of release factor rf1, trnas and mrna bound to the ribosome and is described in remark 400 2b9n 
50s ribosomal subunit from a crystal structure of release factor rf2, trnas and mrna bound to the ribosome. this file contains the 50s subunit from a crystal structure of release factor rf1, trnas and mrna bound to the ribosome and is described in remark 400. 2b9p 
50s ribosomal subunit from a crystal structure of the ribosome in complex with trnas and mrna with a stop codon in the a-site. this file contains the 50s subunit from a crystal structure of the ribosome in complex with trnas and mrna with a stop codon in the a-site and is described in remark 400. 2bcw 
Coordinates of the n-terminal domain of ribosomal protein l11,c-terminal domain of ribosomal protein l7/l12 and a portion of the g' domain of elongation factor g, as fitted into cryo-em map of an escherichia coli 70s*ef- g*gdp*fusidic acid complex 2e34 
L11 structure with rdc and rg refinement 2e35 
The minimized average structure of l11 with rg refinement 2e36 
L11 with sans refinement 2fow 
The rna binding domain of ribosomal protein l11: three- dimensional structure of the rna-bound form of the protein, nmr, 26 structures 2ftc 
Structural model for the large subunit of the mammalian mitochondrial ribosome 2gya 
Structure of the 50s subunit of a pre-translocational e. coli ribosome obtained by fitting atomic models for rna and protein components into cryo-em map emd-1056 2gyc 
Structure of the 50s subunit of a secm-stalled e. coli ribosome complex obtained by fitting atomic models for rna and protein components into cryo-em map emd-1143 2h8w 
Solution structure of ribosomal protein l11 2hgj 
Crystal structure of the 70s thermus thermophilus ribosome showing how the 16s 3'-end mimicks mrna e and p codons. this entry 2hgj contains 50s ribosomal subunit. the 30s ribosomal subunit can be found in pdb entry 2hgi. 2hgq 
Crystal structure of the 70s thermus thermophilus ribosome with translocated and rotated shine-dalgarno duplex. this entry 2hgq contains 50s ribosomal subunit. the 30s ribosomal subunit can be found in pdb entry 2hgp. 2hgu 
70s t.th. ribosome functional complex with mrna and e- and p-site trnas at 4.5a. this entry 2hgu contains 50s ribosomal subunit. the 30s ribosomal subunit can be found in pdb entry 2hgr. 2i2t 
Crystal structure of ribosome with messenger rna and the anticodon stem-loop of p-site trna. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2i2v 
Crystal structure of ribosome with messenger rna and the anticodon stem-loop of p-site trna. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2j01 
Structure of the thermus thermophilus 70s ribosome complexed with mrna, trna and paromomycin (part 2 of 4). this file contains the 50s subunit from molecule i. 2j03 
Structure of the thermus thermophilus 70s ribosome complexed with mrna, trna and paromomycin (part 4 of 4). this file contains the 50s subunit from molecule ii. 2j28 
Model of e. coli srp bound to 70s rncs 2jq7 
Model for thiostrepton binding to the ribosomal l11-rna 2k3f 
Ribosomal protein l11 from thermotoga maritima 2klm 
Solution structure of l11 with saxs and rdc 2nxn 
T. thermophilus ribosomal protein l11 methyltransferase (prma) in complex with ribosomal protein l11 2otj 
13-deoxytedanolide bound to the large subunit of haloarcula marismortui 2otl 
Girodazole bound to the large subunit of haloarcula marismortui 2qa4 
A more complete structure of the the l7/l12 stalk of the haloarcula marismortui 50s large ribosomal subunit 2qam 
Crystal structure of the bacterial ribosome from escherichia coli in complex with neomycin. this file contains the 50s subunit of the first 70s ribosome, with neomycin bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qao 
Crystal structure of the bacterial ribosome from escherichia coli in complex with neomycin. this file contains the 50s subunit of the second 70s ribosome, with neomycin bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qba 
Crystal structure of the bacterial ribosome from escherichia coli in complex with gentamicin. this file contains the 50s subunit of the first 70s ribosome, with gentamicin bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qbc 
Crystal structure of the bacterial ribosome from escherichia coli in complex with gentamicin. this file contains the 50s subunit of the second 70s ribosome, with gentamicin bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qbe 
Crystal structure of the bacterial ribosome from escherichia coli in complex with ribosome recycling factor (rrf). this file contains the 50s subunit of the first 70s ribosome, with rrf bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qbg 
Crystal structure of the bacterial ribosome from escherichia coli in complex with ribosome recycling factor (rrf). this file contains the 50s subunit of the second 70s ribosome, with rrf bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qbi 
Crystal structure of the bacterial ribosome from escherichia coli in complex with gentamicin and ribosome recycling factor (rrf). this file contains the 50s subunit of the first 70s ribosome, with gentamicin and rrf bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qbk 
Crystal structure of the bacterial ribosome from escherichia coli in complex with gentamicin and ribosome recycling factor (rrf). this file contains the 50s subunit of the second 70s ribosome, with gentamicin and rrf bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2qex 
Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit 2qov 
Crystal structure of the bacterial ribosome from escherichia coli in complex with spectinomycin. this file contains the 50s subunit of the first 70s ribosome. the entire crystal structure contains two 70s ribosomes. 2qox 
Crystal structure of the bacterial ribosome from escherichia coli in complex with spectinomycin. this file contains the 50s subunit of the second 70s ribosome. the entire crystal structure contains two 70s ribosomes. 2qoz 
Crystal structure of the bacterial ribosome from escherichia coli in complex with spectinomycin and neomycin. this file contains the 50s subunit of the first 70s ribosome, with neomycin bound. the entire crystal structure contains two 70s ribosomes. 2qp1 
Crystal structure of the bacterial ribosome from escherichia coli in complex with spectinomycin and neomycin. this file contains the 50s subunit of the second 70s ribosome, with neomycin bound. the entire crystal structure contains two 70s ribosomes. 2rdo 
50s subunit with ef-g(gdpnp) and rrf bound 2vhm 
Structure of pdf binding helix in complex with the ribosome (part 1 of 4) 2vhn 
Structure of pdf binding helix in complex with the ribosome. (part 2 of 4) 2wh2 
Insights into translational termination from the structure of rf2 bound to the ribosome 2wh4 
Insights into translational termination from the structure of rf2 bound to the ribosome 2wrj 
The structure of the ribosome with elongation factor g trapped in the post-translocational state (part 2 of 4). 2wrl 
The structure of the ribosome with elongation factor g trapped in the post-translocational state. (part 4 of 4). 2z4l 
Crystal structure of the bacterial ribosome from escherichia coli in complex with paromomycin and ribosome recycling factor (rrf). this file contains the 50s subunit of the first 70s ribosome, with paromomycin and rrf bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2z4n 
Crystal structure of the bacterial ribosome from escherichia coli in complex with paromomycin and ribosome recycling factor (rrf). this file contains the 50s subunit of the second 70s ribosome, with paromomycin and rrf bound. the entire crystal structure contains two 70s ribosomes and is described in remark 400. 2zjp 
Thiopeptide antibiotic nosiheptide bound to the large ribosomal subunit of deinococcus radiodurans 2zjq 
Interaction of l7 with l11 induced by microccocin binding to the deinococcus radiodurans 50s subunit 2zjr 
Refined native structure of the large ribosomal subunit (50s) from deinococcus radiodurans 2zkr 
Structure of a mammalian ribosomal 60s subunit within an 80s complex obtained by docking homology models of the rna and proteins into an 8.7 a cryo-em map 3bbo 
Homology model for the spinach chloroplast 50s subunit fitted to 9.4a cryo-em map of the 70s chlororibosome 3cc2 
The refined crystal structure of the haloarcula marismortui large ribosomal subunit at 2.4 angstrom resolution with rrna sequence for the 23s rrna and genome-derived sequences for r-proteins 3cc4 
Co-crystal structure of anisomycin bound to the 50s ribosomal subunit 3cc7 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u 3cce 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a 3ccj 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u 3ccl 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model. 3ccm 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u 3ccq 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u 3ccr 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model. 3ccs 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a 3ccu 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c 3ccv 
Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a 3cd6 
Co-cystal of large ribosomal subunit mutant g2616a with cc- puromycin 3cf5 
Thiopeptide antibiotic thiostrepton bound to the large ribosomal subunit of deinococcus radiodurans 3cjq 
Ribosomal protein l11 methyltransferase (prma) in complex with dimethylated ribosomal protein l11 in space group p212121 3cjr 
Ribosomal protein l11 methyltransferase (prma) in complex with ribosomal protein l11 (k39a) and inhibitor sinefungin. 3cjs 
Minimal recognition complex between prma and ribosomal protein l11 3cjt 
Ribosomal protein l11 methyltransferase (prma) in complex with dimethylated ribosomal protein l11 3cma 
The structure of cca and cca-phe-cap-bio bound to the large ribosomal subunit of haloarcula marismortui 3cme 
The structure of ca and cca-phe-cap-bio bound to the large ribosomal subunit of haloarcula marismortui 3deg 
Complex of elongating escherichia coli 70s ribosome and ef4(lepa)-gmppnp 3df2 
Crystal structure of the bacterial ribosome from escherichia coli in complex with hygromycin b. this file contains the 50s subunit of the first 70s ribosome. the entire crystal structure contains two 70s ribosomes. 3df4 
Crystal structure of the bacterial ribosome from escherichia coli in complex with hygromycin b. this file contains the 50s subunit of the second 70s ribosome. the entire crystal structure contains two 70s ribosomes. 3dll 
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect trna positioning 3e1b 
Structure of the 50s subunit of e. coli ribosome in pre- accommodation state 3e1d 
Structure of the 50s subunit of e. coli ribosome in post- accommodation state 3egv 
Ribosomal protein l11 methyltransferase (prma) in complex with trimethylated ribosomal protein l11 3ep2 
Model of phe-trna(phe) in the ribosomal pre-accommodated state revealed by cryo-em 3eq3 
Model of trna(trp)-ef-tu in the ribosomal pre-accommodated state revealed by cryo-em 3eq4 
Model of trna(leu)-ef-tu in the ribosomal pre-accommodated state revealed by cryo-em 3f1f 
Crystal structure of a translation termination complex formed with release factor rf2. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes as described in remark 400. 3f1h 
Crystal structure of a translation termination complex formed with release factor rf2. this file contains the 50s subunit of the second 70s ribosome. the entire crystal structure contains two 70s ribosomes as described in remark 400. 3fik 
Ternary complex-bound e.coli 70s ribosome. this entry consists of the 50s subunit. 3fin 
T. thermophilus 70s ribosome in complex with mrna, trnas and ef-tu.gdp.kirromycin ternary complex, fitted to a 6.4 a cryo-em map. this file contains the 50s subunit. 3g4s 
Co-crystal structure of tiamulin bound to the large ribosomal subunit 3g6e 
Co-crystal structure of homoharringtonine bound to the large ribosomal subunit 3g71 
Co-crystal structure of bruceantin bound to the large ribosomal subunit 3i1n 
Crystal structure of the e. coli 70s ribosome in an intermediate state of ratcheting 3i1p 
Crystal structure of the e. coli 70s ribosome in an intermediate state of ratcheting 3i1r 
Crystal structure of the e. coli 70s ribosome in an intermediate state of ratcheting 3i1t 
Crystal structure of the e. coli 70s ribosome in an intermediate state of ratcheting 3i20 
Crystal structure of the e. coli 70s ribosome in an intermediate state of ratcheting 3i22 
Crystal structure of the e. coli 70s ribosome in an intermediate state of ratcheting 3iy9 
Leishmania tarentolae mitochondrial large ribosomal subunit model 487d 
Seven ribosomal proteins fitted to a cryo-electron microscopic map of the large 50s subunit at 7.5 angstroms resolution - Links (links to other resources describing this domain)
-
PFAM Ribosomal_L11 INTERPRO IPR000911