MITMicrotubule Interacting and Trafficking molecule domain
|SMART accession number:||SM00745|
|Interpro abstract (IPR007330):|
The MIT domain forms an asymmetric three-helix bundle. It is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking.
A 'variant' MIT domain has been described at the N-terminal region of a related AAA-ATPase, mammalian katanin p60 [(PUBMED:20339000)].
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- Evolution (species in which this domain is found)
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- Structure (3D structures containing this domain)
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