NPCBM

NPCBM
SMART accession number:SM00776
Description: This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins.
Interpro abstract (IPR013222):

This entry represents a putative carbohydrate binding module (NPCBM) domain found at the N terminus of glycosyl hydrolase family 98 proteins [(PUBMED:16212961)].

Proteins containing this domain include CpGH98 from C. perfringens. It specifically hydrolyses fucose-containing trisaccharides from the glycotopes of blood groups A and B and is implicated for the infectivity and virulence of this pathogen [(PUBMED:15618227)]. CpGH98 has a central TIM barrel catalytic domain, in which putative catalytic residues may be tentatively identified, and an N-terminal novel putative carbohydrate binding module (NPCBM) [(PUBMED:15618227)].

Family alignment:
View or

There are 396 NPCBM domains in 285 proteins in SMART's nrdb database.

Click on the following links for more information.