Spc7

Spc7 kinetochore protein
Spc7
SMART accession number:SM00787
Description: This domain is found in cell division proteins which are required for kinetochore-spindle association.
Interpro abstract (IPR013253):

This domain is found in cell division proteins which are required for kinetochore-spindle association [ (PUBMED:15371542) ]. Proteins containing this domain include budding yeast Spc105 and fission yeast Spc7.

Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex, which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle [ (PUBMED:22711988) ]. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [ (PUBMED:19893618) ].

Family alignment:
View or

There are 277 Spc7 domains in 277 proteins in SMART's nrdb database.

Click on the following links for more information.