Amelin

Ameloblastin precursor (Amelin)
Amelin
SMART accession number:SM00817
Description: This family consists of several mammalian Ameloblastin precursor (Amelin) proteins. Matrix proteins of tooth enamel consist mainly of amelogenin but also of non-amelogenin proteins, which, although their volumetric percentage is low, have an important role in enamel mineralisation. One of the non-amelogenin proteins is ameloblastin, also known as amelin and sheathlin. Ameloblastin (AMBN) is one of the enamel sheath proteins which is though to have a role in determining the prismatic structure of growing enamel crystals.
Interpro abstract (IPR007798): This family consists of mammalian Ameloblastin precursor (Amelin) proteins. Matrix proteins of tooth enamel consist mainly of amelogenin but also of non-amelogenin proteins, which, although their volumetric percentage is low, have an important role in enamel mineralization. One of the non-amelogenin proteins is ameloblastin, also known as amelin and sheathlin. Ameloblastin (AMBN) is one of the enamel sheath proteins which is thought to have a role in determining the prismatic structure of growing enamel crystals [(PUBMED:11867231)].
GO process:odontogenesis of dentin-containing tooth (GO:0042475)
GO function:structural constituent of tooth enamel (GO:0030345)
Family alignment:
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There are 20 Amelin domains in 20 proteins in SMART's nrdb database.

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