Robl_LC7

Roadblock/LC7 domain
Robl_LC7
SMART accession number:SM00960
Description: This family includes proteins that are about 100 amino acids long and have been shown to be related (PUBMED:11084347). Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions (PUBMED:10402468). This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility (PUBMED:2464581). However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.
Interpro abstract (IPR004942):

This family includes proteins that are about 100 amino acids long and have been shown to be related [(PUBMED:11084347)]. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions [(PUBMED:10402468)]. This family also includes Golgi-associated MP1 adapter protein (Q9Y2Q5) and MglB from Myxococcus xanthus (Q50883), a protein involved in gliding motility [(PUBMED:2464581)]. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.

Family alignment:
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There are 2897 Robl_LC7 domains in 2888 proteins in SMART's nrdb database.

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