TRCF |
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| SMART accession number: | SM00982 |
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| Description: | This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the transcription-repair-coupling factor (TRCF) which releases RNAP and the truncated transcript. |
| Interpro abstract (IPR005118): | This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the transcription-repair-coupling factor (TRCF) which releases RNAP and the truncated transcript. |
| GO process: | DNA repair (GO:0006281) |
| GO function: | damaged DNA binding (GO:0003684), helicase activity (GO:0004386), ATP binding (GO:0005524) |
| Family alignment: |
There are 1757 TRCF domains in 1757 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
- Cellular role (predicted cellular role)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)
to expand nodes. To display all proteins with a TRCF domain in a specific node, click on it.
