CarD_TRCF

CarD-like/TRCF domain
CarD_TRCF
SMART accession number:SM01058
Description: CarD is a Myxococcus xanthus protein required for the activation of light- and starvation-inducible genes (PUBMED:8692912). This family includes the presumed N-terminal domain. CarD interacts with the zinc-binding protein CarG, to form a complex that regulates multiple processes in Myxococcus xanthus (PUBMED:16879646). This family also includes a domain to the N-terminal side of the DEAD helicase of TRCF proteins. TRCF displaces RNA polymerase stalled at a lesion, binds to the damage recognition protein UvrA, and increases the template strand repair rate during transcription (PUBMED:7876261). This domain is involved in binding to the stalled RNA polymerase (PUBMED:7876261).
Interpro abstract (IPR003711):

CarD is a Myxococcus xanthus protein required for the activation of light- and starvation-inducible genes [(PUBMED:8692912)]. This entry represents a domain found in the N terminus of CarD. It is also found in transcription-repair-coupling factor (TRCF) proteins.

Family alignment:
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There are 8314 CarD_TRCF domains in 8314 proteins in SMART's nrdb database.

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