Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

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DM13 Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9.

SMART accession number:	SM00686
Description:	-
Interpro abstract (IPR019545):	The DM13 domain has been identified in animal proteins containing a DOMON domain likely to function as cytochromes involved in as yet unidentified redox reactions potentially related to protein hydroxylation or oxidative cross-linking. However, it is also found in bacteria. The DM13 domain contains a nearly absolutely conserved cysteine, which can be potentially involved in a redox reaction either as a nacked thiol group or by binding a prosthetic group like heme [ (PUBMED:17878204) ]. The DM13 domain is predicted to have a beta-strand-rich fold [ (PUBMED:17878204) ].
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 1343 DM13 domains in 668 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing DM13 domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with DM13 domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing DM13 domain in the selected taxonomic class.

• Metabolism (metabolic pathways involving proteins which contain this domain)

• Click the image to view the interactive version of the map in iPath

  % proteins involved KEGG pathway ID Description 100.00 map00350 Tyrosine metabolism This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with DM13 domain which could be assigned to a KEGG orthologous group, and not all proteins containing DM13 domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

• Links (links to other resources describing this domain)

• INTERPRO	IPR019545

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