BRCT

breast cancer carboxy-terminal domain
BRCT
SMART accession number:SM00292
Description: -
Interpro abstract (IPR001357):

The BRCT domain (after the C_terminal domain of a breast cancer susceptibility protein) is found predominantly in proteins involved in cell cycle checkpoint functions responsive to DNA damage [(PUBMED:9034168)], for example as found in the breast cancer DNA-repair protein BRCA1. The domain is an approximately 100 amino acid tandem repeat, which appears to act as a phospho-protein binding domain [(PUBMED:14576433)].

Family alignment:
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There are 20377 BRCT domains in 14800 proteins in SMART's nrdb database.

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