DUF106

Integral membrane protein DUF106
DUF106
SMART accession number:SM01415
Description: This archaebacterial protein family has no known function. Members are predicted to be integral membrane proteins.
Interpro abstract (IPR002809):

This entry represents a group of eukaryotic and archaeal proteins. Eukaryotic members include EMC3, a subunit of the ER membrane protein complex (EMC) required for protein folding [(PUBMED:19325107)], and TMCO1, a ER calcium load-activated calcium channel [(PUBMED:27212239)]. Archaeal members may function as insertases of the archaeal plasma membrane [(PUBMED:26256539)].

GO component:membrane (GO:0016020)
Family alignment:
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There are 3039 DUF106 domains in 3036 proteins in SMART's nrdb database.

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