DUF1785 |
 |
|---|
| SMART accession number: | SM01163
|
|---|
| Description: |
This region is found in argonaute [(PUBMED:16216572)] proteins and often co-occurs with BAG (SM00264) and Piwi (SM00950). |
|---|
| Family alignment: |
|
|---|
There are 504
DUF1785 domains in 503 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
-
- Literature (relevant references for this domain)
-
Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Hall TM
- Structure and function of argonaute proteins.
- Structure. 2005; 13: 1403-8
- Display abstract
Argonaute (Ago) family proteins are multidomain proteins expressed in prokaryoticand eukaryotic organisms. In eukaryotes, Ago proteins are most well known fortheir roles in RNA silencing. In prokaryotes, the functions of Ago proteins areunknown, but based on their similarity to eukaryotic Ago proteins, they could be involved in nucleic acid-directed regulatory pathways related to RNA silencing.Recent structural and biochemical studies have shed new light on the function of this family of proteins. These studies reveal how these proteins recognize andcleave RNA and suggest a function for prokaryotic family members.
- Links (links to other resources describing this domain)
-
to expand nodes. To display all proteins with a DUF1785 domain in a specific node, click on it.