Schultz et al. (1998) Proc. Natl. Acad. Sci. USA 95, 5857-5864
Letunic et al. (2012) Nucleic Acids Res , doi:10.1093/nar/gkr931

• HOME
• SETUP
• FAQ
• ABOUT
• GLOSSARY
• WHAT'S NEW
• FEEDBACK

ENT

SMART accession number:	SM01191
Description:	This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown function. This domain has a completely conserved histidine residue that may be functionally important.
Family alignment:	View or CHROMA formatCLUSTALW formatMSF formatFASTA formatPIR format

There are 163 ENT domains in 160 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Click on to expand nodes. To display all proteins with a ENT domain in a specific node, click on it.

  This tree shows only several representative species. The complete taxonomic breakdown of all proteins with ENT domain is also avaliable.

  Useful shortcuts: Expand all nodes or Collapse tree
  Go to specific node: Anopheles gambiae, Arabidopsis thaliana, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus, Takifugu rubripes

• Structure (3D structures containing this domain)

• 3D Structures of ENT domains in PDB

  PDB code	Main view	Title
  1utu		Crystal structure of novel protein emsy truncate
  1uz3		Crystal structure of novel protein emsy
  2fmm		Crystal structure of emsy-hp1 complex

• Links (links to other resources describing this domain)

• PFAM	ENT

Send comments to Ivica Letunic