EXOIII

EXOIII
SMART accession number:SM00479
Description: exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other exonucleases
Interpro abstract (IPR006055): This entry includes a variety of exonuclease proteins, such as ribonuclease T [(PUBMED:8506149)] and the epsilon subunit of DNA polymerase III. Ribonuclease T is responsible for the end-turnover of tRNA,and removes the terminal AMP residue from uncharged tRNA. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria, and also exhibits 3' to 5' exonuclease activity.
GO function:exonuclease activity (GO:0004527)
Family alignment:
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There are 18660 EXOIII domains in 18613 proteins in SMART's nrdb database.

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