FANCL C-terminal domain
SMART accession number:SM01197
Description: This domain is found at the C-terminus of the Fancl protein in humans which is the putative E3 ubiquitin ligase subunit of the FA complex (Fanconi anaemia). Eight subunits of the Fanconi anaemia gene products form a multisubunit nuclear complex which is required for mono-ubiquitination of a downstream FA protein, FANCD2.
Family alignment:
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There are 188 FANCL_C domains in 187 proteins in SMART's nrdb database.

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