|SMART accession number:||SM01244|
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- Evolution (species in which this domain is found)
Taxonomic distribution of proteins containing IRS domain.
This tree includes only several representative species. The complete taxonomic breakdown of all proteins with IRS domain is also avaliable.
Click on the protein counts, or double click on taxonomic names to display all proteins containing IRS domain in the selected taxonomic class.
- Structure (3D structures containing this domain)
3D Structures of IRS domains in PDB
PDB code Main view Title 1irs IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE 1j0w Crystal Structure Analysis of the Dok-5 PTB Domain 1mix Crystal structure of a FERM domain of Talin 1miz Crystal structure of an integrin beta3-talin chimera 1mk7 CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA 1mk9 CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA 1p5t Crystal Structure of Dok1 PTB Domain 1qqg CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1 1uef Crystal Structure of Dok1 PTB Domain Complex 1xr0 Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors 1y19 Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions 2dlw Solution structure of the IRS domain of human docking protein 2, isoform a 2g35 NMR structure of talin-PTB in complex with PIPKI 2h7d Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide 2h7e Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide- minimized average structure 2k00 Solution structure of the talin F3 in complex with layilin cytodomain 2kgx HADDOCK structure of the talin F3 domain in complex with talin 1655-1822 2kup Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK 2kuq Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK 2mfq NMR solution structures of FRS2a PTB domain with neurotrophin receptor TrkB 2v76 Crystal structure of the human dok1 PTB domain 2ys5 Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK 2yt2 Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK 3g9w Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail 3ivf Crystal structure of the talin head FERM domain 3ml4 Crystal structure of a complex between Dok7 PH-PTB and the MuSK juxtamembrane region 4f7g Crystal structure of talin autoinhibition complex
- Links (links to other resources describing this domain)