PAN_AP

divergent subfamily of APPLE domains
PAN_AP
SMART accession number:SM00473
Description: Apple-like domains present in Plasminogen, C. elegans hypothetical ORFs and the extracellular portion of plant receptor-like protein kinases. Predicted to possess protein- and/or carbohydrate-binding functions.
Interpro abstract (IPR003609): The apple domain, IPR000177, has an N-terminal region that contains four tandem repeats of about 90 amino acids and a C-terminal catalytic domain. The 90 amino-acid repeated domain contains 6 conserved cysteines. It has been shown [(PUBMED:1998666)] that three disulphide bonds link the first and sixth, second and fifth, and third and fourth cysteines. This entry contains apple-like domains, which are presented in Plasminogen, Caenorhabditis elegans hypothetical ORFs and the extracellular portion of plant S-locus glycoproteins (IPR000858) and S-receptor kinases. The domain is predicted to possess protein- and/or carbohydrate-binding functions.
Family alignment:
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There are 3592 PAN_AP domains in 2502 proteins in SMART's nrdb database.

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