POLXcDNA polymerase X family |
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| SMART accession number: | SM00483 |
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| Description: | includes vertebrate polymerase beta and terminal deoxynucleotidyltransferases |
| Interpro abstract (IPR002054): | DNA carries the biological information that instructs cells how to exist in an ordered fashion: accurate replication is thus one of the most important events in the cell life cycle. This function is mediated by DNA-directed DNA-polymerases, which add nucleotide triphosphate (dNTP) residues to the 5'-end of the growing DNA chain, using a complementary DNA as template. Small RNA molecules are generally used as primers for chain elongation, although terminal proteins may also be used. Three motifs, A, B and C [(PUBMED:2196557)], are seen to be conserved across all DNA-polymerases, with motifs A and C also seen in RNA- polymerases. They are centred on invariant residues, and their structural significance was implied from the Klenow (Escherichia coli) structure: motif A contains a strictly-conserved aspartate at the junction of a beta-strand and an alpha-helix; motif B contains an alpha-helix with positive charges; and motif C has a doublet of negative charges, located in a beta-turn-beta secondary structure [(PUBMED:2196557)]. DNA polymerases (EC 2.7.7.7) can be classified, on the basis of sequence similarity [(PUBMED:3479792), (PUBMED:2196557)], into at least four different groups: A, B, C and X. Members of family X are small (about 40 kDa) compared with other polymerases and encompass two distinct polymerase enzymes that have similar functionality: vertebrate polymerase beta (same as yeast pol 4), and terminal deoxynucleotidyl-transferase (TdT) (EC 2.7.7.31). The former functions in DNA repair, while the latter terminally adds single nucleotides to polydeoxynucleotide chains. Both enzymes catalyse addition of nucleotides in a distributive manner, i.e. they dissociate from the template-primer after addition of each nucleotide. DNA-polymerases show a degree of structural similarity with RNA-polymerases. This domain is found either at the extreme N or C termini of DNA polymerase X proteins. |
| GO function: | DNA-directed DNA polymerase activity (GO:0003887), DNA binding (GO:0003677) |
| Family alignment: |
There are 553 POLXc domains in 553 proteins in SMART's nrdb database.
Click on the following links for more information.
- Evolution (species in which this domain is found)
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Go to specific node: Arabidopsis thaliana, Homo sapiens, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae, Takifugu rubripes - Literature (relevant references for this domain)
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Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Pelletier H, Sawaya MR, Kumar A, Wilson SH, Kraut J
- Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.
- Science. 1994; 264: 1891-903
- Display abstract
Two ternary complexes of rat DNA polymerase beta (pol beta), a DNA template-primer, and dideoxycytidine triphosphate (ddCTP) have been determined at 2.9 A and 3.6 A resolution, respectively. ddCTP is the triphosphate of dideoxycytidine (ddC), a nucleoside analog that targets the reverse transcriptase of human immunodeficiency virus (HIV) and is at present used to treat AIDS. Although crystals of the two complexes belong to different space groups, the structures are similar, suggesting that the polymerase-DNA-ddCTP interactions are not affected by crystal packing forces. In the pol beta active site, the attacking 3'-OH of the elongating primer, the ddCTP phosphates, and two Mg2+ ions are all clustered around Asp190, Asp192, and Asp256. Two of these residues, Asp190 and Asp256, are present in the amino acid sequences of all polymerases so far studied and are also spatially similar in the four polymerases--the Klenow fragment of Escherichia coli DNA polymerase I, HIV-1 reverse transcriptase, T7 RNA polymerase, and rat DNA pol beta--whose crystal structures are now known. A two-metal ion mechanism is described for the nucleotidyl transfer reaction and may apply to all polymerases. In the ternary complex structures analyzed, pol beta binds to the DNA template-primer in a different manner from that recently proposed for other polymerase-DNA models.
- Metabolism (metabolic pathways involving proteins which contain this domain)
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% proteins involved KEGG pathway ID Description 100.00 map04640 Hematopoietic cell lineage This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with POLXc domain which could be assigned to a KEGG orthologous group, and not all proteins containing POLXc domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.
- Structure (3D structures containing this domain)
3D Structures of POLXc domains in PDB
PDB code Main view Title 1bpb 
Crystal structure of rat dna polymerase beta: evidence for a common polymerase mechanism 1bpd 
Crystal structure of rat dna polymerase beta: evidence for a common polymerase mechanism 1bpe 
Crystal structure of rat dna polymerase beta; evidence for a common polymerase mechanism 1bpx 
Dna polymerase beta/dna complex 1bpy 
Human dna polymerase beta complexed with gapped dna and ddctp 1bpz 
Human dna polymerase beta complexed with nicked dna 1huo 
Crystal structure of dna polymerase beta complexed with dna and cr-tmppcp 1huz 
Crystal structure of dna polymerase complexed with dna and cr-pcp 1jms 
Crystal structure of the catalytic core of murine terminal deoxynucleotidyl transferase 1jn3 
Fidelity properties and structure of m282l mutator mutant of dna polymerase: subtle structural changes influence the mechanism of nucleotide discrimination 1kdh 
Binary complex of murine terminal deoxynucleotidyl transferase with a primer single stranded dna 1kej 
Crystal structure of murine terminal deoxynucleotidyl transferase complexed with ddatp 1mq2 
Human dna polymerase beta complexed with gapped dna containing an 8-oxo-7,8-dihydro-guanine and damp 1mq3 
Human dna polymerase beta complexed with gapped dna containing an 8-oxo-7,8-dihydro-guanine template paired with dctp 1nom 
Dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the presence of mncl2 (5 millimolar) 1rpl 
2.3 angstroms crystal structure of the catalytic domain of dna polymerase beta 1rzt 
Crystal structure of dna polymerase lambda complexed with a two nucleotide gap dna molecule 1tv9 
Human dna polymerase beta complexed with nicked dna containing a mismatched template adenine and incoming cytidine 1tva 
Human dna polymerase beta complexed with nicked dna containing a mismatched template thymidine and incoming cytidine 1xsl 
Crystal structure of human dna polymerase lambda in complex with a one nucleotide dna gap 1xsn 
Crystal structure of human dna polymerase lambda in complex with a one nucleotide dna gap and ddttp 1xsp 
Crystal structure of human dna polymerase lambda in complex with nicked dna and pyrophosphate 1zjm 
Human dna polymerase beta complexed with dna containing an a-a mismatched primer terminus 1zjn 
Human dna polymerase beta complexed with dna containing an a-a mismatched primer terminus with dgtp 1zqa 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of kcl (150 millimolar) at ph 7.5 1zqb 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of bacl2 (150 millimolar) 1zqc 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of cacl2 (15 millimolar) 1zqd 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of cacl2 (150 millimolar) 1zqe 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of crcl3 (saturated solution) 1zqf 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of cscl (150 millimolar) 1zqg 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of a sodium-free artificial mother liquor at ph 6.5 1zqh 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of a sodium-free artificial mother liquor at ph 7.5 1zqi 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of kcl (150 millimolar) 1zqj 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of cacl2 (15 millimolar) and mgcl2 (15 millimolar) 1zqk 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of kcl (75 millimolar) and mgcl2 (75 millimolar) 1zql 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of mncl2 (15 millimolar) and mgcl2 (15 millimolar) 1zqm 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of mncl2 (15 millimolar) 1zqn 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of bacl2 (15 millimolar) and nacl (15 millimolar) 1zqo 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of cacl2 (15 millimolar) and nacl (15 millimolar) 1zqp 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of kcl (75 millimolar) and nacl (75 millimolar) 1zqq 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of mncl2 (15 millimolar) and nacl (15 millimolar) 1zqr 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of nicl2 1zqs 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of tlcl (0.5 millimolar) 1zqt 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (0.01 millimolar) and zncl2 (0.02 millimolar) 1zqu 
Dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the presence of artificial mother liquor 1zqv 
Dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the presence of cacl2 (150 millimolar) 1zqw 
Dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the presence of cscl (150 millimolar) 1zqx 
Dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the presence of kcl (150 millimolar) 1zqy 
Dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the presence of mgcl2 (50 millimolar) 1zqz 
Dna polymerase beta (pol b) (e.c.2.7.7.7), 31-kd domain; soaked in the presence of mncl2 (50 millimolar) 2bcq 
Dna polymerase lambda in complex with a dna duplex containing an unpaired dtmp 2bcr 
Dna polymerase lambda in complex with a dna duplex containing an unpaired damp 2bcs 
Dna polymerase lambda in complex with a dna duplex containing an unpaired dcmp 2bcu 
Dna polymerase lambda in complex with a dna duplex containing an unpaired damp and a t:t mismatch 2bcv 
Dna polymerase lambda in complex with dttp and a dna duplex containing an unpaired dtmp 2bpc 
Crystal structure of rat dna polymerase beta: evidence for a common polymerase mechanism 2bpf 
Structures of ternary complexes of rat dna polymerase beta, a dna template-primer, and ddctp 2bpg 
Structures of ternary complexes of rat dna polymerase beta, a dna template-primer, and ddctp 2fmp 
Dna polymerase beta with a terminated gapped dna substrate and ddctp with sodium in the catalytic site 2fmq 
Sodium in active site of dna polymerase beta 2fms 
Dna polymerase beta with a gapped dna substrate and dumpnpp with magnesium in the catalytic site 2gws 
Crystal structure of human dna polymerase lambda with a g/g mismatch in the primer terminus 2i9g 
Dna polymerase beta with a benzo[c]phenanthrene diol epoxide adducted guanine base 2ihm 
Polymerase mu in ternary complex with gapped 11mer dna duplex and bound incoming nucleotide 2iso 
Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma- difluoromethylene triphosphate 2isp 
Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma- methylene triphosphate 2p66 
Human dna polymerase beta complexed with tetrahydrofuran (abasic site) containing dna 2pfn 
Na in the active site of dna polymerase lambda 2pfo 
Dna polymerase lambda in complex with dna and dupnpp 2pfp 
Dna polymerase lambda in complex with dna and dctp 2pfq 
Manganese promotes catalysis in a dna polymerase lambda-dna crystal 2pxi 
Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma- monofluoromethylene triphosphate 2van 
Nucleotidyl transfer mechanism of mismatched dntp incorporation by dna polymerase b by structural and kinetic analyses 2w9m 
Structure of family x dna polymerase from deinococcus radiodurans 3c2k 
Dna polymerase beta with a gapped dna substrate and dumpnpp with manganese in the active site 3c2l 
Ternary complex of dna polymerase beta with a c:dapcpp mismatch in the active site 3c2m 
Ternary complex of dna polymerase beta with a g:dapcpp mismatch in the active site 3c5f 
Structure of a binary complex of the r517a pol lambda mutant 3c5g 
Structure of a ternary complex of the r517k pol lambda mutant 3gdx 
Dna polymerase beta with a gapped dnd substrate and dtmp(cf2)pp 3hw8 
Ternary complex of dna polymerase lambda of a two nucleotide gapped dna substrate with a c in the scrunch site 3hwt 
Ternary complex of dna polymerase lambda bound to a two nucleotide gapped dna substrate with a scrunched da 3hx0 
Ternary complex of l277a, h511a, r514 mutant pol lambda bound to a 2 nucleotide gapped dna substrate with a scrunched da 3isb 
Binary complex of human dna polymerase beta with a gapped dna 3isc 
Binary complex of human dna polymerase beta with an abasic site (thf) in the gapped dna 3isd 
Ternary complex of human dna polymerase beta with an abasic site (thf): dapcpp mismatch 7ice 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of cacl2 7icf 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of cdcl2 (0.1 millimolar) (four-day soak) 7icg 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of cdcl2 7ich 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of cocl2 7ici 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of crcl3 (0.1 millimolar) 7icj 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of cucl2 (0.1 millimolar) 7ick 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of mgcl2 7icl 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of mncl2 (0.1 millimolar) 7icm 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of mncl2 (1.0 millimolar) 7icn 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of nicl2 7ico 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of zncl2 7icp 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of zncl2 (0.01 millimolar) 7icq 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of zncl2 7icr 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of zncl2 7ics 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of zncl2 7ict 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of zncl2 and mgcl2 7icu 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of cdcl2 (0.1 millimolar) 7icv 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of mncl2 (0.1 millimolar) and in the absence of nacl 8ica 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar) and cacl2 (5 millimolar) 8icb 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of artificial mother liquor 8icc 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna (no 5'-phosphate) 8ice 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar) and cdcl2 (1 millimolar) 8icf 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (10 millimolar) and mgcl2 (50 millimolar) 8icg 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar) and mgcl2 (5 millimolar) 8ich 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dctp (1 millimolar) and mgcl2 (5 millimolar) 8ici 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dgtp (1 millimolar) and mgcl2 (5 millimolar) 8icj 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + thymidine- 5'-triphosphate, soaked in the presence of dttp and mgcl2 8ick 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar), mgcl2 (5 millimolar), and mncl2 (5 millimolar) 8icl 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar) and nicl2 (5 millimolar) 8icm 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar), mncl2 (5 millimolar), and ammonium sulfate (75 millimolar) 8icn 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of atp (1 millimolar) and mncl2 (5 millimolar) 8ico 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of azt-tp (1 millimolar) and mncl2 (5 millimolar) 8icp 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar) and mncl2 (5 millimolar) 8icq 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of of datp (0.1 millimolar) and mncl2 (0.5 millimolar) 8icr 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar) and mncl2 (5 millimolar) 8ics 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dctp (1 millimolar) and mncl2 (5 millimolar) 8ict 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dctp (1 millimolar) and mncl2 (5 millimolar) 8icu 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of ddatp (1 millimolar) and mncl2 (5 millimolar) 8icv 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dgtp (1 millimolar) and mncl2 (5 millimolar) 8icw 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dttp (1 millimolar) and mncl2 (5 millimolar) 8icx 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dttp (1 millimolar) and mncl2 (5 millimolar) 8icy 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + thymidine- 5'-triphosphate, soaked in the presence of dttp and mncl2 8icz 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of of datp (1 millimolar), mncl2 (5 millimolar), and lithium sulfate (75 millimolar) 9ica 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2'- deoxyadenosine-5'-o-(1-thiotriphosphate), soaked in the presence of datp(alpha)s and mncl2 9icb 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2'- deoxyadenosine-5'-triphosphate, soaked in the presence of datp and cocl2 9icc 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2'- deoxyadenosine-5'-triphosphate, soaked in the presence of datp and crcl3 9ice 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of datp (1 millimolar) and cucl2 (0.1 millimolar) 9icf 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2'- deoxyadenosine-5'-triphosphate, soaked in the presence of datp and zncl2 9icg 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dctp (1 millimolar) and zncl2 (1 millimolar) 9ich 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dgtp (1 millimolar) and zncl2 (1 millimolar) 9ici 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna; soaked in the presence of dttp (1 millimolar) and zncl2 (1 millimolar) 9icj 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with seven base pairs of dna 9ick 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of artificial mother liquor 9icl 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of pyrophosphate and mncl2 9icm 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of double stranded dna (no 5'-phosphate) 9icn 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2',3'- dideoxycytidine-5'-triphosphate, soaked in the presence of ddctp and mgcl2 9ico 
Dna polymerase beta (e.c.2.7.7.7)/dna complex, soaked in the presence of dttp and mgcl2 9icp 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of pyrophosphate (1 millimolar) and mgcl2 (5 millimolar) 9icq 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of datp (1 millimolar) and mncl2 (5 millimolar) 9icr 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2'- deoxycytidine-5'-triphosphate, soaked in the presence of dctp and mncl2 9ics 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2',3'- dideoxycytidine-5'-triphosphate, soaked in the presence of ddctp and mncl2 9ict 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2'- deoxyguanosine-5'-triphosphate, soaked in the presence of dgtp and mncl2 9icu 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; soaked in the presence of dttp (1 millimolar) and mncl2 (5 millimolar) 9icv 
Dna polymerase beta (e.c.2.7.7.7)/dna complex + 2'- deoxyadenosine-5'-triphosphate, soaked in the presence of datp and zncl2 9icw 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna; native structure 9icx 
Dna polymerase beta (pol b) (e.c.2.7.7.7) complexed with six base pairs of dna (non gapped dna only) 9icy 
Dna polymerase beta (e.c.2.7.7.7) complexed with seven base pairs of dna (non gapped dna only) - Links (links to other resources describing this domain)
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PFAM DNA_polymeraseX INTERPRO IPR002054 PROSITE DNA_POLYMERASE_X