Pro-kuma_activ

Pro-kumamolisin, activation domain
Pro-kuma_activ
SMART accession number:SM00944
Description: This domain is found at the N-terminus of peptidases belonging to MEROPS peptidase family S53 (sedolisin, clan SB). The domain adopts a ferredoxin-like fold, with an alpha+beta sandwich. Cleavage of the domain results in activation of the peptidase (PUBMED:15242607).
Interpro abstract (IPR015366):

This domain is found at the N terminus of peptidases belonging to MEROPS peptidase family S53 (sedolisin, clan SB). The domain adopts a ferredoxin-like fold, with an alpha+beta sandwich. Cleavage of the domain results in activation of the peptidase [(PUBMED:15242607)].

GO function:serine-type peptidase activity (GO:0008236)
Family alignment:
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There are 6403 Pro-kuma_activ domains in 6400 proteins in SMART's nrdb database.

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