Schultz et al. (1998) Proc. Natl. Acad. Sci. USA 95, 5857-5864
Letunic et al. (2008) Nucleic Acids Res , doi:10.1093/nar/gkn808

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DM10 Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases.

There are 365 DM10 domains in 152 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Click on to expand nodes. To display all proteins with a DM10 domain in a specific node, click on it.

  This tree shows only several representative species. The complete taxonomic breakdown of all proteins with DM10 domain is also avaliable.

  Useful shortcuts: Expand all nodes or Collapse tree
  Go to specific node: Anopheles gambiae, Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus, Takifugu rubripes

• Cellular role (predicted cellular role)

• Cellular role: transcription
  Binding / catalysis: unknown

• Metabolism (metabolic pathways involving proteins which contain this domain)

• Click the image to view the interactive version of the map in iPath

  % proteins involved KEGG pathway ID Description 50.00 map00240 Pyrimidine metabolism 50.00 map00230 Purine metabolism This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with DM10 domain which could be assigned to a KEGG orthologous group, and not all proteins containing DM10 domain. Please note that proteins can be included in multiple pathways, ie. the numbers above will not always add up to 100%.

• Structure (3D structures containing this domain)

• 3D Structures of DM10 domains in PDB

  PDB code	Main view	Title
  2z13		Crystal structure of the n-terminal duf1126 in human ef- hand domain
  2z14		Crystal structure of the n-terminal duf1126 in human ef- hand domain containing 2 protein

• Links (links to other resources describing this domain)

• INTERPRO	IPR006602