AIP3

Actin interacting protein 3
AIP3
SMART accession number:SM00806
Description: Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in Saccharomyces cerevisiae that was previously identified as an actin-interacting protein. Actin-interacting protein 3 (Aip3p) localizes at the cell cortex where cytoskeleton assembly must be achieved to execute polarized cell growth, and deletion of AIP3 causes gross defects in cell and cytoskeletal polarity. Aip3p localization is mediated by the secretory pathway, mutations in early- or late-acting components of the secretory apparatus lead to Aip3p mislocalization (PUBMED:10679021).
Interpro abstract (IPR005613):

Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in Saccharomyces cerevisiae (Baker's yeast) that was previously identified as an actin-interacting protein. Actin-interacting protein 3 (Aip3p) localizes at the cell cortex where cytoskeleton assembly must be achieved to execute polarised cell growth, and deletion of AIP3 causes gross defects in cell and cytoskeletal polarity. Aip3p localisation is mediated by the secretory pathway, mutations in early- or late-acting components of the secretory apparatus lead to Aip3p mislocalisation [(PUBMED:10679021)].

This entry represents AIP3 fungi proteins.

Family alignment:
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There are 68 AIP3 domains in 68 proteins in SMART's nrdb database.

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