Agenet

Tudor-like domain present in plant sequences.
Agenet
SMART accession number:SM00743
Description: Domain in plant sequences with possible chromatin-associated functions.
Interpro abstract (IPR014002):

This entry represents an agenet domain found in EMSY-like (AtEML) proteins, which have possible roles in chromatin regulation and are related to the BRCA2-interacting human oncoprotein EMSY [ (PUBMED:21830950) ]. Proteins containing this domain also include MRG2 (AT1G02740) from Arabidopsis and PHD finger protein 20-like protein 1 (PHF20L1) from animals. MRG2 binds to the FLOWERING LOCUS T locus and elevates the expression in an H3K36me3-dependent manner [ (PUBMED:25183522) ]. The function of PHF20L1 is not clear.

Family alignment:
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There are 8129 Agenet domains in 3554 proteins in SMART's nrdb database.

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