Ami_2

Ami_2
SMART accession number:SM00644
Description:
Interpro abstract (IPR002502): Proteins families containing this domain include zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC 3.5.1.28 This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the Bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.
GO process:peptidoglycan catabolic process (GO:0009253)
GO function:N-acetylmuramoyl-L-alanine amidase activity (GO:0008745)
Family alignment:
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There are 2419 Ami_2 domains in 2395 proteins in SMART's nrdb database.

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