BLUF

Sensors of blue-light using FAD
BLUF
SMART accession number:SM01034
Description: The BLUF domain has been shown to bind FAD in the AppA protein (Q53119). AppA is involved in the repression of photosynthesis genes in response to blue-light.
Interpro abstract (IPR007024): The BLUF domain (named for sensors of Blue-Light Using FAD) is an FAD-binding protein domain. BLUF domains are present in various proteins, primarily from bacteria. For example a BLUF domain is found at the N terminus of the AppA protein from Rhodobacter sphaeroides [(PUBMED:16323221)]. BLUF domains are involved in sensing blue-light (and possibly redox) using FAD, and are similar to the flavin-binding PAS domains and cryptochromes. Their predicted secondary structure reveals that the BLUF domains have a novel FAD-binding fold [(PUBMED:12368079)].
GO function:FAD binding (GO:0071949), blue light photoreceptor activity (GO:0009882)
Family alignment:
View or

There are 379 BLUF domains in 359 proteins in SMART's nrdb database.

Click on the following links for more information.