CADDomains present in proteins implicated in post-mortem DNA fragmentation
|SMART accession number:||SM00266|
|Interpro abstract (IPR003508):|
This domain consists of caspase-activated (CAD) nucleases, which induce DNA fragmentation and chromatin condensation during apoptosis, and the cell death activator proteins CIDE-A and CIDE-B, which are inhibitors of CAD nuclease. The two proteins interact through the region defined by the method signatures.
|GO process:||apoptotic process (GO:0006915)|
|GO component:||intracellular (GO:0005622)|
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- Evolution (species in which this domain is found)
- Metabolism (metabolic pathways involving proteins which contain this domain)
- Structure (3D structures containing this domain)
- Links (links to other resources describing this domain)