CADGDystroglycan-type cadherin-like domains.
|SMART accession number:||SM00736|
|Description:||Cadherin-homologous domains present in metazoan dystroglycans and alpha/epsilon sarcoglycans, yeast Axl2p and in a very large protein from magnetotactic bacteria. Likely to bind calcium ions.|
|Interpro abstract (IPR006644):|
In animals, cadherin domain-containing proteins are adhesion molecules that modulate a wide variety of processes including cell polarization and migration but they have also been identified in yeast and magnetotactic bacteria. Crystal structures have revealed that multiple cadherin domains form Ca2+-dependent rod-like structures with a conserved Ca2+-binding pocket at the domain-domain interface [(PUBMED:11909544)].
|GO component:||membrane (GO:0016020)|
|GO function:||calcium ion binding (GO:0005509)|
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- Evolution (species in which this domain is found)
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- Structure (3D structures containing this domain)
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