CADG

Dystroglycan-type cadherin-like domains.
CADG
SMART accession number:SM00736
Description: Cadherin-homologous domains present in metazoan dystroglycans and alpha/epsilon sarcoglycans, yeast Axl2p and in a very large protein from magnetotactic bacteria. Likely to bind calcium ions.
Interpro abstract (IPR006644):

In animals, cadherin domain-containing proteins are adhesion molecules that modulate a wide variety of processes including cell polarization and migration but they have also been identified in yeast and magnetotactic bacteria. Crystal structures have revealed that multiple cadherin domains form Ca2+-dependent rod-like structures with a conserved Ca2+-binding pocket at the domain-domain interface [(PUBMED:11909544)].

GO component:membrane (GO:0016020)
GO function:calcium ion binding (GO:0005509)
Family alignment:
View or

There are 1314 CADG domains in 455 proteins in SMART's nrdb database.

Click on the following links for more information.