Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

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CDC37_C Cdc37 C terminal domain

SMART accession number:	SM01069
Description:	Cdc37 is a protein required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the C terminal domain whose function is unclear. It is found C terminal to the Hsp90 chaperone (Heat shocked protein 90) binding domain PF08565 and the N terminal kinase binding domain of Cdc37 (PUBMED:16098195).
Interpro abstract (IPR013873):	Cdc37 is a protein required for the activity of numerous eukaryotic protein kinases. This entry corresponds to the C-terminal domain whose function is unclear. It is found C-terminal to the Hsp90 chaperone (heat shock protein 90) binding domain ( IPR013874 ) and the N-terminal kinase binding domain of Cdc37 ( IPR013855 ) [ (PUBMED:16098195) ].
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 1390 CDC37_C domains in 1387 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing CDC37_C domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with CDC37_C domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing CDC37_C domain in the selected taxonomic class.

• Structure (3D structures containing this domain)

• 3D Structures of CDC37_C domains in PDB

  PDB code	Main view	Title
  1us7		Complex of Hsp90 and P50
  2n5x		2N5X
  5fwk		5FWK
  5fwl		5FWL
  5fwm		5FWM
  5fwp		5FWP

• Links (links to other resources describing this domain)

• PFAM	CDC37_C
  INTERPRO	IPR013873

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