Schultz et al. (1998) Proc. Natl. Acad. Sci. USA 95, 5857-5864
Letunic et al. (2012) Nucleic Acids Res , doi:10.1093/nar/gkr931

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CFEM

SMART accession number:	SM00747
Description:	eight cysteine-containing domain present in fungal extracellular membrane proteins
Interpro abstract (IPR014005):	The CFEM domain contains eight cysteines and is found in fungal extracellular membrane proteins.
Family alignment:	View or CHROMA formatCLUSTALW formatMSF formatFASTA formatPIR format

There are 54 CFEM domains in 29 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Click on to expand nodes. To display all proteins with a CFEM domain in a specific node, click on it.

  This tree shows only several representative species. The complete taxonomic breakdown of all proteins with CFEM domain is also avaliable.

  Useful shortcuts: Expand all nodes or Collapse tree
  

• Literature (relevant references for this domain)

• Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.

  • Kulkarni RD, Kelkar HS, Dean RA
  • An eight-cysteine-containing CFEM domain unique to a group of fungal membrane proteins.
  • Trends Biochem Sci. 2003; 28: 118-21
  • Display abstract

  • CFEM, an eight cysteine-containing domain, has been identified by analyzing over 25 fungal sequences selected from database sequence searches. Features of CFEM suggest that it is a novel domain with characteristics distinct from known cysteine-rich domains. Some CFEM-containing proteins (e.g. Pth11 from Magnaporthe grisea) are proposed to have important roles in fungal pathogenesis.

  • Kulkarni RD, Kelkar HS, Dean RA
  • An eight-cysteine-containing CFEM domain unique to a group of fungalmembrane proteins.
  • Trends Biochem Sci. 2003; 28: 118-21
  • Display abstract

  • CFEM, an eight cysteine-containing domain, has been identified byanalyzing over 25 fungal sequences selected from database sequencesearches. Features of CFEM suggest that it is a novel domain withcharacteristics distinct from known cysteine-rich domains. SomeCFEM-containing proteins (e.g. Pth11 from Magnaporthe grisea) are proposedto have important roles in fungal pathogenesis.

• Links (links to other resources describing this domain)

• INTERPRO	IPR014005

Send comments to Ivica Letunic