SMART accession number:SM01122
Description: DBC1 and it homologs from diverse eukaryotes are a catalytically inactive version of the Nudix hydrolase (MutT) domain ((PUBMED:18418069)). DBC1 is predicted to bind NAD metabolites and regulate the activity of SIRT1 or related deacetylases by sensing the soluble products or substrates of the NAD-dependent deacetylation reaction ((PUBMED:18418069)).
Family alignment:
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There are 297 DBC1 domains in 297 proteins in SMART's nrdb database.

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