DIM1

Mitosis protein DIM1
DIM1
SMART accession number:SM01410
Description: -
Interpro abstract (IPR004123):

This entry represents fission yeast Dim1 and its homologues, including Dib1 from budding yeasts, YLS8 from plants and TXNL4 from animals. Dim1 was originally identified as a mitosis protein [(PUBMED:9182666)]. Later, it was found to interact with spliceosome component Prp6, which is involved in pre-mRNA splicing [(PUBMED:11054566)]. Dim1 may act at the level of mRNA, which impacts the functioning of the APC/C, a critical complex in controlling mitotic progression [(PUBMED:15755920)].

It's worth noting that although the Dim proteins exhibit a thioredoxin-like fold, they lack the disulfide bond required for the thioredoxin redox activity [(PUBMED:17558560)].

GO process:mRNA splicing, via spliceosome (GO:0000398)
GO component:U4/U6 x U5 tri-snRNP complex (GO:0046540)
Family alignment:
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There are 1681 DIM1 domains in 1680 proteins in SMART's nrdb database.

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