Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

• HOME
• SETUP
• FAQ
• ABOUT
• GLOSSARY
• WHAT'S NEW
• FEEDBACK

DUF3385 Domain of unknown function

SMART accession number:	SM01346
Description:	This domain is found in eukaryotes.
Interpro abstract (IPR024585):	This uncharacterised domain is is typically between 160 to 172 amino acids in length. It is found in the phosphatidylinositol kinase-related protein kinases TOR (target of rapamycin). In Saccharomyces cerevisiae the TOR proteins, TOR1 and TOR2, regulate growth in a rapamycin-sensitive manner [ (PUBMED:12408816) ].
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 1788 DUF3385 domains in 1786 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing DUF3385 domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with DUF3385 domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing DUF3385 domain in the selected taxonomic class.

• Structure (3D structures containing this domain)

• 3D Structures of DUF3385 domains in PDB

  PDB code	Main view	Title
  5fvm		5FVM

• Links (links to other resources describing this domain)

• INTERPRO	IPR024585
  PFAM	DUF3385

Send comments to Ivica Letunic