This domain is required for the nuclear localisation of these proteins (PUBMED:11352458). All of these proteins are members of the Tale/Knox homeodomain family, a subfamily within homeobox SM00389.
Family alignment:
There are 386
ELK domains in 280 proteins in SMART's nrdb database.
Click on the following links for more information.
Evolution (species in which this domain is found)
Click on to expand nodes. To display all proteins with a ELK domain in a specific node, click on it.
This tree shows only several representative species. The complete taxonomic breakdown of all proteins with ELK domain is also avaliable.
Expression of a class 1 knotted1-like homeobox gene is down-regulated in peacompound leaf primordia.
Plant Mol Biol. 2001; 45: 387-98
Display abstract
Differences in knotted1-like (knox) gene expression may account for some of thediversity of leaf forms seen in nature. Class 1 knox genes are expressed in thecompound leaf primordia of tomato but not in the simple leaf primordia of a rangeof species examined so far. In order to test the hypothesis that all compoundleaves differ from simple leaves in this way, we isolated a class 1 knox cDNAfrom pea, Pskn1 (Pisum sativum knotted1) and examined its expression pattern. Theencoded homeodomain of Pskn1 shares 88% identical residues with KNOTTED1 frommaize and an adjacent ELK domain is present. The protein sequence of PSKN1 is 69%identical to TKN2, its nearest related sequence in tomato. Unlike TKn2, Pskn1 wasnot expressed in newly initiated compound leaves. The expression pattern of Pskn1resembled those of other class 1 knox genes described in maize and Arabidopsis.Transcripts were detected in the shoot apical meristem and developing vasculatureof the vegetative shoot, but expression was not detected in newly initiated anddeveloping compound leaf primordia. The same pattern of expression was observedin the afila mutant, which is characterised by highly ramified compound leaves.Our results suggest that tomato and pea use different developmental processes in the generation of their compound leaves.
Links (links to other resources describing this domain)
to expand nodes. To display all proteins with a ELK domain in a specific node, click on it.