EsV_1_7EsV-1-7 repeat |
) |
|---|
| SMART accession number: | SM01425
|
|---|
| Description: |
The EsV-1-7 repeat is a cysteine-rich motif of unknown function. The EsV-1-7 repeat motif was originally identified in the Ectocarpus IMMEDIATE UPRIGHT protein, which has an EsV-1-7 domain that contains five EsV-1-7 repeats (PMID: 28049657). The name is derived from the Ectocarpus virus EsV-1 protein EsV-1-7, which possesses six EsV-1-7 repeats. Ectocarpus has a large family of 91 EsV-1-7 domain proteins with between one and 19 copies of the motif (C-X4-C-X16-C-X2-H-X12). In addition to brown algae, EsV-1-7 domain proteins have been found in eustigmatophytes, oomycetes, cryptophytes, two families of green algae (Coccomyxaceae and Selenastraceae) and in two additional viral genomes, Emiliania huxleyi virus PS401 and Pithovirus sibericum. Based on this unusual distribution, it has been proposed that EsV-1-7 domain genes have been exchanged between lineages by horizontal gene transfer during evolution (PMID: 28049657). |
|---|
| Family alignment: |
|
|---|
There are 0 EsV_1_7 domains in 0 proteins in SMART's nrdb database.
Click on the following links for more information.
Literature (relevant references for this domain)
Primary literature is listed below; Automatically-derived, secondary literature is also avaliable.
- Macaisne N et al.
- The Ectocarpus IMMEDIATE UPRIGHT gene encodes a member of a novel family ofcysteine-rich proteins with an unusual distribution across the eukaryotes.
- Development. 2017; 144: 409-418
- Display abstract
The sporophyte generation of the brown alga Ectocarpus sp. exhibits an unusualpattern of development compared with the majority of brown algae. The first cell division is symmetrical and the apical-basal axis is established late indevelopment. In the immediate upright (imm) mutant, the initial cell undergoes anasymmetric division to immediately establish the apical-basal axis. We provideevidence which suggests that this phenotype corresponds to the ancestral state ofthe sporophyte. The IMM gene encodes a protein of unknown function that contains a repeated motif also found in the EsV-1-7 gene of the Ectocarpus virus EsV-1.Brown algae possess large families of EsV-1-7 domain genes but these genes arerare in other stramenopiles, suggesting that the expansion of this family mighthave been linked with the emergence of multicellular complexity. EsV-1-7 domaingenes have a patchy distribution across eukaryotic supergroups and occur inseveral viral genomes, suggesting possible horizontal transfer during eukaryoteevolution.
