FDF

FDF
SMART accession number:SM01199
Description: The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C terminus of Scd6p-like SM domains. It is also found with other divergent Sm domains and in proteins such as Dcp3p and FLJ21128, where it is found N terminal to the YjeF-N domain, a novel Rossmann fold domain PMID 15257761.
Interpro abstract (IPR019050):

The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops [(PUBMED:15257761)]. It is found at the C terminus of Scd6p-like SM domains [(PUBMED:15257761), (PUBMED:15225602)]. It is also found with other divergent Sm domains and in proteins such as Dcp3p and FLJ21128, where it is found N-terminal to the YjeF-N domain, a novel Rossmann fold domain [(PUBMED:15257761)].

Family alignment:
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There are 3917 FDF domains in 3915 proteins in SMART's nrdb database.

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