Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922
Letunic et al. (2020) Nucleic Acids Res doi: 10.1093/nar/gkaa937

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GCK

SMART accession number:	SM01227
Description:	This domain is found in proteins carrying other domains known to be involved in intracellular signalling pathways indicating that it might also be involved in these pathways. It has 4 highly conserved cysteine residues, suggesting that it can bind zinc ions. Moreover, it is found repeated in some members of this family. This may indicate that these domains are able to interact with one another, raising the possibility that this domain mediates heterodimerisation.
Family alignment:	View or CHROMA formatHMM/Web logoCLUSTALW formatMSF formatFASTA formatPIR format

There are 401 GCK domains in 357 proteins in SMART's nrdb database.

Click on the following links for more information.

• Evolution (species in which this domain is found)

• Taxonomic distribution of proteins containing GCK domain.

  This tree includes only several representative species. The complete taxonomic breakdown of all proteins with GCK domain is also avaliable.

  Click on the protein counts, or double click on taxonomic names to display all proteins containing GCK domain in the selected taxonomic class.

• Cellular role (predicted cellular role)

• Cellular role: signalling
  

• Links (links to other resources describing this domain)

• PFAM	GCK

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