GED

Dynamin GTPase effector domain
GED
SMART accession number:SM00302
Description: -
Interpro abstract (IPR003130):

Dynamin GTPase effector domain found in proteins related to dynamin.

Dynamin is a GTP-hydrolysing protein that is an essential participant in clathrin-mediated endocytosis by cells. It self-assembles into 'collars' in vivo at the necks of invaginated coated pits; the self-assembly of dynamin being coordinated by the GTPase domain. Mutation studies indicate that dynamin functions as a molecular regulator of receptor-mediated endocytosis [(PUBMED:10206643)].

GO function:GTP binding (GO:0005525), GTPase activity (GO:0003924)
Family alignment:
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There are 1795 GED domains in 1785 proteins in SMART's nrdb database.

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