H4

Histone H4
H4
SMART accession number:SM00417
Description:
Interpro abstract (IPR001951): Histone H4 is one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core. Along with H3, it plays a central role in nucleosome formation. The sequence of histone H4 has remained almost invariant in more then 2 billion years of evolution [(PUBMED:8121801), (PUBMED:6808351), (PUBMED:3340182)].
GO process:nucleosome assembly (GO:0006334)
GO component:nucleus (GO:0005634), nucleosome (GO:0000786)
GO function:DNA binding (GO:0003677)
Family alignment:
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There are 362 H4 domains in 362 proteins in SMART's nrdb database.

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