HTH_LACI

helix_turn _helix lactose operon repressor
HTH_LACI
SMART accession number:SM00354
Description:
Interpro abstract (IPR000843): Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR [(PUBMED:1639817), (PUBMED:1805309)]. Within this family, the HTH motif is situated towards the N terminus.
GO process:regulation of transcription, DNA-dependent (GO:0006355)
GO component:intracellular (GO:0005622)
GO function:sequence-specific DNA binding transcription factor activity (GO:0003700)
Family alignment:
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There are 8985 HTH_LACI domains in 8977 proteins in SMART's nrdb database.

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